BCAA 500mg Capsules
BCAA 500mg Capsules
$15.57 - $16.39
Builds muscle, increases metabolism, and initiates protein synthesis!*
Quantity Discount Price
1-4
$0.00
$16.39
5+
5%
$15.57
SKU: 9927

The "branched chain" amino acids (BCAA's), leucine, isoleucine and valine are so called because the side chains of these amino acids (the part of the molecule that differentiates the amino acids) are made up of non-linear (branching) carbon chains. The BCAA's are essential amino acids, meaning that they must be consumed in the diet (rather than manufactured in the body) and constitute a more than one third of the amino acid composition of skeletal muscle(1). During high intensity exercise, the BCAA's are oxidized for use as fuel and to maintain oxidative metabolite concentration(2). Supplementing with BCAA's reduces exercise-induced muscle proteolysis (breakdown)(3) and also stimulates muscle protein synthesis(4). Daily BCAA supplementation may also reduce muscle damage, promote strength recovery and even enhance blood oxygen carrying capacity(5).

Of the three BCAA's, leucine plays a special role in skeletal muscle metabolism, in particular by exerting an anti-catabolic and anabolic effect on protein metabolism(6-10). Leucine metabolites that have been sold as sports (HMB) or animal feed supplements (keto-isocaproate) also exert anabolic effects in humans and growing animals(11, 12). In fact, leucine incorporation into skeletal muscle has long been used as a marker of muscle protein synthesis(13) and oxidation(14). Because leucine so powerfully stimulates muscle protein synthesis, some researchers have suggested leucine supplementation to combat age-associated loss of skeletal muscle mass (sarcopenia)(9).

Directions

As a dietary supplement, take 1 Serving (4 Capsules) between meals, 30-45 minutes before workouts, and/or immediately after workouts.

Ingredients

Active Ingredients

L-Leucine, L-Isoleucine, L-Valine.

Inactive Ingredients

Magnesium Stearate (Vegetable), Capsule (Vegetable Cellulose).

General Warnings

If you are currently pregnant or nursing, consult a physician prior to use. Keep out of the reach of children.

Allergen Warnings

Although this product may not contain one or all of the following, this product is manufactured in a facility that handles milk, soy, egg, peanut, nut, tree, fish, crustaceans/shellfish, and wheat products.

DISCLAIMER: The above description is provided for information only and does not constitute medical advice. Please consult your physician or the appropriately licensed professional before engaging in a program of exercise or nutritional supplementation. No information in this site has been reviewed by the FDA. No product is intended to treat, diagnose, or cure any disease.

References

1. Harper, A.E., et al., Branched-chain amino acid metabolism. Annu Rev Nutr, 1984. 4: p. 409-54. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6380539

2. Gibala, M.J., Regulation of skeletal muscle amino acid metabolism during exercise. Int J Sport Nutr Exerc Metab, 2001. 11(1): p. 87-108. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11255139

3. Tang, F.C., Influence of branched-chain amino acid supplementation on urinary protein metabolite concentrations after swimming. J Am Coll Nutr, 2006. 25(3): p. 188-94. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16766776

4. Shimomura, Y., et al., Exercise promotes BCAA catabolism: effects of BCAA supplementation on skeletal muscle during exercise. J Nutr, 2004. 134(6 Suppl): p. 1583S-1587S. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15173434

5. Ohtani, M., et al., Amino acid mixture improves training efficiency in athletes. J Nutr, 2006. 136(2): p. 538S-543S. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16424143

6. Goldberg, A.L., Protein synthesis during work-induced growth of skeletal muscle. J Cell Biol, 1968. 36: p. 653-658.

7. Goldberg, A.L. and H.M. Goodman, Amino acid transport during work-induced growth of skeletal muscle. Am J Physiol, 1969. 216: p. 1111-1115.

8. Goldberg, A.L., et al., Mechanism of work-induced hypertrophy of skeletal muscle. Med Sci.Sports, 1975. 7: p. 185-198.

9. Fujita, S. and E. Volpi, Amino acids and muscle loss with aging. J Nutr, 2006. 136(1 Suppl): p. 277S-80S. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16365098

10. Kimball, S.R. and L.S. Jefferson, Signaling pathways and molecular mechanisms through which branched-chain amino acids mediate translational control of protein synthesis. J Nutr, 2006. 136(1 Suppl): p. 227S-31S.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16365087

11. Flakoll, P.J., et al., Influence of alpha-ketoisocaproate on lamb growth, feed conversion, and carcass composition. J Anim Sci, 1991. 69(4): p. 1461-7.

12. Nissen, S., et al., Effect of leucine metabolite beta-hydroxy-beta-methylbutyrate on muscle metabolism during resistance-exercise training. J. Appl. Physiol., 1996. 81(5): p. 2095-104.

13. Nair, K.S., et al., Leucine incorporation into mixed skeletal muscle protein in humans. Am J Physiol, 1988. 254(2 Pt 1): p. E208-13. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3279803

14. Boirie, Y., et al., Slow and fast dietary proteins differently modulate postprandial protein accretion. Proc Natl Acad Sci U S A, 1997. 94(26): p. 14930-5. http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/referer?http://www.pnas.org/cgi/content/full/94/26/14930


Customer Reviews
(5.00)
# of Ratings: 1
1. on 7/8/2014, said:
AMAZING PRODUCT, take one pre workout, no taste, super easy to take, and if you know me, im all about connivence
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Serving Size 1 (4Ca)
Servings Per Container 50
Amount Per Serving
% Daily Value*
Branched Chain Amino Acids (L-Leucine, L-Isoleucine, L-Valine) 2000mg
**
** Percent Daily Values not established.

The above statement has not been evaluated by the FDA. This product is not intended to diagnose or treat any disease.
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